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. 2021 Oct 11;10(12):1177–1185. doi: 10.1002/open.202100131

Table 1.

Synthesis of compounds 3 af.

graphic file with name OPEN-10-1177-g002.jpg

Compound

R1

R2

Yield [%]

3 a

−CH3

H

85

3 b

−CH3

F

47

3 c

−CH2−CH3

F

61

3 d

−(CH2)2−CH3

F

49

3 e

−N(CH2)4

F

54

3 f

−N(CH3)2

F

57