. Author manuscript; available in PMC: 2022 May 1.

Published in final edited form as: Crit Care Med. 2021 May 1;49(5):e521–e532. doi: 10.1097/CCM.0000000000004920

Table 3:

Motoric Subtypes vs. Functional Outcomes

3-month follow up (N=556)	ADL Odds Ratio (95% CI)	IADL-FAQ Difference (95% CI)
Hypoactive Delirium	1.05 (1.00, 1.12)	0.24 (0.07, 0.41)
Hyperactive Delirium	0.94 (0.80, 1.10)	0.17 (−0.31, 0.66)
12-month follow up (N=474)	ADL Odds Ratio (95% CI)	IADL-FAQ Difference (95% CI)
Hypoactive Delirium	1.06 (1.00, 1.12)	0.11 (−0.07, 0.29)
Hyperactive Delirium	0.89 (0.73, 1.08)	−0.09 (−0.58, 0.40)

After adjusting for potential baseline and in-hospital confounders including age, gender, race, education, comorbidities, baseline cognitive and functional impairment, history of depression, severity of illness, and days of coma and mechanical ventilation, hypoactive delirium was associated with worse disability in IADLs at 3 months with a 0.24 point increase in FAQ score for each additional day of hypoactive delirium, or 1 additional disability for every 4 days of hypoactive delirium. We did not find a significant association between hypoactive or hyperactive delirium and the odds of developing a new disability in ADLs at 3 or 12 months, nor did we find an association between IADLs and hypoactive delirium at 12 months or hyperactive delirium at 3 or 12 months.