Table 1.
Characteristics of Cases with Tubulointerstitial Nephritis with Uveitis
| Characteristic | Result |
|---|---|
| Number cases | 94 |
| Demographics | |
| Age, median, years (25th 75th percentile) | 17 (13, 42) |
| Age category, years (%) | |
| ≤16 | 46 |
| 17–50 | 33 |
| 51–59 | 7 |
| ≥60 | 12 |
| Missing | 2 |
| Gender (%) | |
| Men | 36 |
| Women | 64 |
| Race/ethnicity (%) | |
| White, non-Hispanic | 70 |
| Black, non-Hispanic | 5 |
| Hispanic | 7 |
| Asian, Pacific Islander | 4 |
| Other | 4 |
| Missing/unknown | 8 |
| Uveitis History | |
| Uveitis course (%) | |
| Acute, monophasic | 14 |
| Acute, recurrent | 6 |
| Chronic | 60 |
| Indeterminate | 20 |
| Laterality (%) | |
| Unilateral | 14 |
| Unilateral, alternating | 0 |
| Bilateral | 86 |
| Ophthalmic examination | |
| Cornea | |
| Normal | 100 |
| Keratitis | 0 |
| Keratic precipitates (%) | |
| None | 49 |
| Fine | 40 |
| Round | 4 |
| Stellate | 2 |
| Mutton Fat | 4 |
| Other | 0 |
| Anterior chamber cells (%) | |
| Grade ½+ | 16 |
| 1+ | 30 |
| 2+ | 31 |
| 3+ | 16 |
| 4+ | 7 |
| Hypopyon (%) | 0 |
| Anterior chamber flare (%) | |
| Grade 0 | 55 |
| 1+ | 28 |
| 2+ | 14 |
| 3+ | 2 |
| 4+ | 1 |
| Iris (%) | |
| Normal | 68 |
| Posterior synechiae | 32 |
| Sectoral iris atrophy | 0 |
| Patchy iris atrophy | 0 |
| Diffuse iris atrophy | 0 |
| Heterochromia | 0 |
| Intraocular pressure (IOP), involved eyes | |
| Median, mm Hg (25th, 75th percentile) | 14 (12, 17) |
| Proportion patients with IOP>24 mm Hg either eye (%) | 1 |
| Vitreous cells (%) | |
| Grade 0 | 30 |
| ½+ | 27 |
| 1+ | 32 |
| 2+ | 5 |
| 3+ | 6 |
| 4+ | 0 |
| Vitreous haze (%) | |
| Grade 0 | 81 |
| ½+ | 7 |
| 1+ | 4 |
| 2+ | 6 |
| 3+ | 1 |
| 4+ | 1 |
| Vitreous snowballs | 0 |
| Choroidal lesions | 2 |
| Laboratory (%) | |
| Elevated serum creatinine | 58 |
| Elevated serum creatinine among cases with results reported | 89 |
| Elevated urine β-2 microglobulin | 23 |
| Elevated urine β-2 microglobulin among cases with results reported | 88 |
| Abnormal urine analysis | 58 |
| Abnormal urine analysis among cases with results reported | 89 |
| Positive renal biopsy | 31 |
| Positive renal biopsy* among cases with biopsy results reported | 100 |
*
Abnormal renal biopsy present in 29/29 cases with biopsy results reported.