Table 3.

Classification Criteria for Tubulointerstitial Nephritis with Uveitis Syndrome

Criteria

1. Evidence of anterior uveitis

a. anterior chamber cells

b. if vitritis or choroiditis or retinal vascular changes are present, anterior chamber inflammation also should be present

AND

2. Evidence of tubulointerstitial nephritis, either

a. Positive renal biopsy OR

b. Elevated urine β-microglobulin and either abnormal urine analysis or elevated serum creatinine

Exclusions

1. Positive serology for syphilis using a treponemal test

2. Evidence of sarcoidosis (either bilateral hilar adenopathy on chest imaging or tissue biopsy demonstrating non-caseating granulomata)