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GM1 ganglioside. Representation of the GM1 structure (A). Minimum energy conformation structure of GM1 (B). Conformation of the GM1 trisaccharide‐β‐GalNAc‐(1‐4)‐[α‐Neu5Ac‐(2‐3)‐]β‐Gal‐; the GM1 trisaccharide behaves as single rigid block because of interactions between the lateral chain and carboxyl group of sialic acid with N‐acetylgalactosamine (C). The two main conformations of the GM1 external disaccharide β‐Gal‐(1‐3)‐β‐GalNAc‐ (D).
