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Effects of caffeic acid on the oxygen affinity of RBCs from a sickle cell patient. Suspensions of SS cell (20% hematocrit) were incubated with 5 mm CA at 0 °C for 48 h prior to determination of the ODC using the Hemox Analyzer. Control is a suspension of SS cells (20% hematocrit).
| Caffeic acid (5 mm) | SS RBCs P50 (mmHg) | Hill coefficient (n) |
|---|---|---|
| SS RBCs (Control) (0) | 46.27 ± 0.27 | 2.94 ± 0.06 |
| SS RBCs + 5 Mm CA | 39.56 ± 1.04 | 2.26 ± 0.11 |
