Table 1.
The baseline characteristics of study cohort.
| Characteristics | Total | FFP transfusion | Non-FFP transfusion |
|---|---|---|---|
| (N = 3,629) | (N = 288) | (N = 3,341) | |
| Gender (men/women) | 2,023/1,606 | 182/106 | 1,841/1,500** |
| Age (years) | 66.6 (53.8–79.7) | 68.4 (54.4–80.6) | 66.4 (53.8–79.6) |
| ≤ 30, n (%) | 175 (4.8) | 10 (3.5) | 165 (4.9) |
| >30, ≤ 60, n (%) | 1,132 (31.2) | 87 (30.2) | 1,045 (31.3) |
| >60, n (%) | 2,322 (64.0) | 191 (66.3) | 2,131 (63.8) |
| Alcohol abuse, n (%) | 388 (10.7) | 41 (14.2) | 347 (10.4)* |
| Culture specimen types | |||
| Blood, n (%) | 1,572 (43.3) | 109 (37.8) | 1,463 (43.8) |
| Lung, n (%) | 122 (3.4) | 8 (2.8) | 114 (3.4) |
| Urinary system, n (%) | 610 (16.8) | 49 (17.0) | 561 (16.8) |
| Gastrointestinal system, n (%) | 11 (0.3) | 0 (0) | 11 (0.3) |
| Others, n (%) | 1,314 (36.2) | 122 (42.4) | 1,192 (35.7)* |
| Culture positive, n (%) | 476 (13.1) | 46 (16.0) | 430 (12.9) |
| Vasopressor (first 24 h), n (%) | 1,082 (29.8) | 101 (35.1) | 981 (29.4)* |
| Mechanical ventilation (first 24 h), n (%) | 1,884 (51.9) | 177 (61.5) | 1,707 (51.1)** |
| Renal replacement therapy, n (%) | 173 (4.8) | 27 (9.4) | 146 (4.4)** |
| GCS score | 15 (13–15) | 15 (14–15) | 15 (13–15)** |
| SOFA score | 5 (3–6) | 6 (4–7) | 4 (3–6)** |
| SAPS II score | 37.0 (30.0–46.0) | 40.5 (34.0–50.0) | 37.0 (29.0–46.0)** |
| Comorbidities | |||
| Congestive heart failure, n (%) | 850 (23.4) | 72 (25.0) | 778 (23.3) |
| Cardiac arrhythmias, n (%) | 1,089 (30.0) | 135 (46.9) | 954 (28.6)** |
| Hypertension, n (%) | 2,140 (59.0) | 159 (55.2) | 1,981 (59.3) |
| Chronic pulmonary, n (%) | 788 (21.7) | 55 (19.1) | 733 (21.9) |
| Renal failure, n (%) | 634 (17.5) | 55 (19.1) | 579 (17.3) |
| Liver disease, n (%) | 347 (9.6) | 57 (19.8) | 290 (8.7)** |
| Solid tumor, n (%) | 231 (6.4) | 23 (8.0) | 208 (6.2) |
| Diabetes, n (%) | 1,043 (28.7) | 78 (27.1) | 965 (28.9) |
| Hospital LOS (days) | 7.7 (4.9–12.7) | 10.4 (6.2–16.5) | 7.6 (4.8–12.4)** |
*
P-value <0.05;
**
P-value <0.01. The data were expressed as median (inter-quartile range) or frequency (percentage). FFP, fresh frozen plasma; GCS, Glasgow coma scale; LOS, length of stay; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment.