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. 2021 Nov 16;8:753297. doi: 10.3389/fvets.2021.753297

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Copyright © 2021 Huang, Chen, Long, Yang, Song, Liu, Li, Liang, Yu, Huang and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Homologous and heterologous immune response of PCV2d Cap protein against the PCV2b and PCV2dagainst the PCV2b and PCV2d. (A) Specific antibody levels for PCV2b and PCV2d Cap proteins at 0 dpc. (B) Detection of PCV2 DNA in serum by PCR at 14 dpc. (C) Detection of the PCV2 DNA load in serum by RT-PCR at 14 dpc. (D) Levels of IFN-γ in blood at 14 dpc. The data are presented as group mean optical density (M_OD ± standard error). Significant differences are indicated by different superscripts (A–C) (p < 0.05). Data were analyzed using one-way analysis of variance with Dunnett's multiple comparisons test using GraphPad Prism 7 software (GraphPad Software, USA), ^****p < 0.001.