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. 2021 Nov 16;11:749003. doi: 10.3389/fonc.2021.749003

Table 2.

Pain scores and additional analgesic requirements.

Variable/ Time points Control group (n = 45) DEX group (n = 46) P value
Pain score (resting/ activity)
 at 1 h after surgery 3 (3–3)/ 3 (3–5) 3 (2–3)/ 3 (3–3) 0.339/ 0.016
 at 24 h after surgery 2 (0–3)/ 4 (2–5) 2 (0–4)/ 3 (2–5) 0.888/ 0.629
 at 48 h after surgery 2 (1–3)/ 3 (2–5) 2 (0–3)/ 3 (2–5) 0.493/ 0.553
Fentanyl administered via intravenous patient-controlled analgesia (μg)
 0–24 h after surgery 462.8 (157.8) 402.2 (148.8) 0.064
 24–48 h after surgery 296.6 (188.7) 303.9 (202.2) 0.860
Additional opioid analgesics requirement (morphine equivalent dose, mg)
 0–1 h after surgery 4.0 (3.2–5.0) (13)* 4.0 (3.0–4.0) (7)* 0.304 (0.102)
 1–24 h after surgery 8.3 (5.0–10.8) (13)* 3.3 (3.3–5.4) (18)* 0.031 (0.303)
 24–48 h after surgery 5.0 (3.3–10.0) (12)* 5.0 (5.0–8.3) (20)* 0.744 (0.093)

Values are median (interquartile range), mean (standard deviation), or number. Pain score, a numerical pain intensity scale (0 = no pain, 10 = the worst pain); *, number of patients receiving additional opioids.