Table 2.
Variable/ Time points | Control group (n = 45) | DEX group (n = 46) | P value |
---|---|---|---|
Pain score (resting/ activity) | |||
at 1 h after surgery | 3 (3–3)/ 3 (3–5) | 3 (2–3)/ 3 (3–3) | 0.339/ 0.016 |
at 24 h after surgery | 2 (0–3)/ 4 (2–5) | 2 (0–4)/ 3 (2–5) | 0.888/ 0.629 |
at 48 h after surgery | 2 (1–3)/ 3 (2–5) | 2 (0–3)/ 3 (2–5) | 0.493/ 0.553 |
Fentanyl administered via intravenous patient-controlled analgesia (μg) | |||
0–24 h after surgery | 462.8 (157.8) | 402.2 (148.8) | 0.064 |
24–48 h after surgery | 296.6 (188.7) | 303.9 (202.2) | 0.860 |
Additional opioid analgesics requirement (morphine equivalent dose, mg) | |||
0–1 h after surgery | 4.0 (3.2–5.0) (13)* | 4.0 (3.0–4.0) (7)* | 0.304 (0.102) |
1–24 h after surgery | 8.3 (5.0–10.8) (13)* | 3.3 (3.3–5.4) (18)* | 0.031 (0.303) |
24–48 h after surgery | 5.0 (3.3–10.0) (12)* | 5.0 (5.0–8.3) (20)* | 0.744 (0.093) |
Values are median (interquartile range), mean (standard deviation), or number. Pain score, a numerical pain intensity scale (0 = no pain, 10 = the worst pain); *, number of patients receiving additional opioids.