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. 2021 Nov 16;9:740574. doi: 10.3389/fcell.2021.740574

FIGURE 1.

FIGURE 1

Schematic diagram of mutual transformation. (A) Organoids: a 3D cell culture, which reproduces the cell composition, morphological structure and other characteristics of the source tissue. (B) Cell lines: a 2D cell culture consisting of a single cell. (C) Xenografts: transplantation of human tissue/cells or directly induced animal models.