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. 2021 Nov 16;8:777145. doi: 10.3389/fmed.2021.777145

Table 3.

Differences and correlations between ROTEM Delta and ClotPro.

n Patients ClotPro ROTEM Δ* p-value r p-value
EX test/EXTEM
CT (s) 95 27 77 (68–85) 86 (75–95) 11 (3–18) <0.001 0.70 <0.001
CFT (s) 95 27 52 (45–76) 60 (49–89) 9 (−4–23) <0.001 0.60 <0.001
alpha 95 27 78 (75–80) 78 (73–80) −1 (−3–1) 0.062 0.66 <0.001
A5 (mm) 95 27 60 (54–63) 58 (47–65) −2 (−6–1) 0.004 0.88 <0.001
A10 (mm) 95 27 66 (62–69) 67 (59–74) 1 (−2–4) 0.028 0.89 <0.001
A20 (mm) 95 27 69 (65–72) 72 (65–77) 3 (0–5) <0.001 0.89 <0.001
MCF (mm) 95 27 70 (66–72) 73 (68–77) 3 (1–5) <0.001 0.88 <0.001
ML (%)§ 69 24 2 (1–3) 4 (2–6) 2 (0–4) <0.001 0.55 <0.001
IN test/INTEM
CT (s) 64 24 165 (155–189) 206 (188–225) 34 (19–54) <0.001 0.53 <0.001
CFT (s) 64 24 57 (50–80) 62 (50–84) 2 (−4–9) 0.074 0.78 <0.001
alpha 64 24 78 (74–80) 78 (73–80) 0 (−2–1) 0.211 0.79 <0.001
A5 (mm) 64 24 54 (46–60) 58 (48–65) 3 (5) <0.001 0.88 <0.001
A10 (mm) 64 24 62 (56–66) 67 (59–73) 5 (4) <0.001 0.87 <0.001
A20 (mm) 64 24 66 (60–69) 72 (66–76) 6 (4) <0.001 0.86 <0.001
MCF (mm) 64 24 67 (63–70) 72 (68–76) 6 (3) <0.001 0.86 <0.001
ML (%)§ 44 21 2 (0–3) 2 (1–4) 0 (0–1) 0.078 0.87 <0.001
FIB test/FIBTEM
CT s 95 27 84 (71–100) 81 (70–91) −1 (−12–4) 0.018 0.71 <0.001
A5 mm 95 27 28 (24–32) 30 (10) 2 (−2–6) <0.001 0.80 <0.001
A10 mm 95 27 30 (26–34) 34 (11) 4 (0–9) <0.001 0.81 <0.001
A20 mm 95 27 32 (28–36) 36 (11) 4 (0–10) <0.001 0.79 <0.001
MCF mm 95 27 35 (29–38) 37 (12) 3 (−1–8) <0.001 0.80 <0.001

Values are mean (SD) and median (25–75th percentile). CT, coagulation time; CFT, clot formation time; alpha, alpha angle; A5, clot amplitude 5 min after CT; A10, clot amplitude 10 min after CT; A20, clot amplitude 20 min after CT; MCF, maximum clot firmness; ML, maximum lysis.

*

Delta.

Wilcoxon signed-rank test.

Spearman correlation coefficient.

§

Only for tests with a runtime of 60 min.