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. 2021 Nov 16;11:636999. doi: 10.3389/fcimb.2021.636999

Table 1.

Demographic characteristics and symptoms of the 1,788 patients with COVID-19.

Covariates All patients, n (%) ALT AST
Normal, n (%) Elevated, n (%) P-value Normal, n (%) Elevated, n (%) P-value
Gender <0.001 0.056
Female 913 (52.50) 833 (91.24) 80 (8.76) 848 (92.88) 65 (7.12)
Male 826 (47.50) 657 (79.54) 169 (20.46) 749 (90.68) 77 (9.32)
Age, median (IQR) 59 (49-68) 60 (49-69) 54 (43-62) <0.001 59 (49-68) 59 (47-69) <0.001
Any comorbidity
Cardiovascular disease 356 (19.91) 317 (89.04) 39 (10.96) 0.040 320 (89.89) 36 (10.11) 0.241
Pulmonary disease 89 (5.12) 79 (88.76) 10 (11.24) 0.394 82 (92.13) 7 (7.87) 0.915
Endocrine disease 137 (7.66) 124 (90.51) 13 (9.49) 0.090 132 (96.35) 5 (3.65) 0.033
Malignancy 64 (3.58) 54 (84.38) 10 (15.63) 0.771 56 (87.50) 8 (12.50) 0.251
Digest system disease 45 (2.52) 37 (82.22) 8 (17.78) 0.510 36 (80.00) 9 (20.00) 0.005
Neurological disease 56 (3.13) 51 (91.07) 5 (8.93) 0.238 49 (87.50) 7 (12.50) 0.284
Initial symptoms
Fever or fatigue 620 (34.68) 516 (83.23) 104 (16.77) 0.035 547 (88.23) 73 (11.77) <0.001
Respiratory symptoms 635 (35.51) 543 (85.51) 92 (14.49) 0.918 568 (89.45) 67 (10.55) 0.025
Digestive symptoms 82 (4.59) 70 (85.37) 12 (14.63) 0.945 72 (87.80) 10 (12.20) 0.228
Neurological symptoms 26 (1.45) 21 (80.77) 5 (19.23) 0.315 23 (88.46) 3 (11.54) 0.483
Other 23 (1.45) 23 (88.46) 3 (11.54) 0.474 26 (100) 0 (0) 0.161