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. 2021 Nov 16;11:636999. doi: 10.3389/fcimb.2021.636999

Table 2.

Laboratory test results of the patients with COVID-19.

Covariate All patientsMedian (IQR)/n (%) ALT AST
Normal Median (IQR)/n (%) Elevated Median (IQR)/n (%) p-value Normal Median (IQR)/n (%) Elevated Median (IQR)/n (%) p-value
Leucocyte count, × 10⁹/L 5.69 (4.70-6.90) 5.63 (4.64-6.84) 6.03 (5.03-7.32) 0.009 5.68 (4.70-6.87) 5.70 (4.81-7.11) 0.084
 3.5-9.5 1592 (89.14) 1362 (85.55) 230 (14.45) 1463 (91.90) 129 (8.10)
 < 3.5 104 (5.82) 97 (93.27) 7 (6.370 93 (89.42) 11 (10.58)
 > 9.5 90 (5.04) 70 (77.78) 20 (22.22) 77 (85.56) 13 (14.44)
Neutrophil count, × 10⁹/L 3.27 (2.53-4.25) 3.24 (2.50-4.23) 3.52 (2.77-4.52) 0.001 3.25 (2.52-6.87) 3.36 (2.61-4.54) 0.012
 1.8-6.3 1558 (87.23) 1336 (85.75) 222 (14.25) 1433 (91.98) 125 (8.02)
 < 1.8 117 (6.55) 109 (93.16) 8 (6.84) 107 (91.45) 10 (8.55)
 > 6.3 111 (6.22) 84 (75.68) 27 (24.32) 93 (83.78) 18 (16.22)
Lymphocyte count, × 10⁹/L 1.60 (1.24-1.99) 1.60 (.24-1.97) 1.64 (1.21-2.04) 0.130 1.62 (1.27-1.99) 1.47 (0.95-1.94) <0.001
 1.1-3.2 1462 (81.86) 1259 (86.11) 203 (13.89) 1361 (93.09) 101 (6.91)
 < 1.1 298 (16.69) 251 (84.23) 47 (15.77) 247 (82.89) 51 (17.11)
 > 3.2 26 (1.46) 19 (73.08) 7 (2.72) 25 (1.53) 1 (3.85)
Erythrocyte count, × 1012/L 4.12 (3.77-4.49) 4.10 (3.73-4.44) 4.32 (3.29-4.75) <0.001 4.12 (13.77-4.49) 4.12 (3.71-4.51) 0.499
 4.3-5.8 639 (35.78) 512 (80.13) 127 (19.87) 583 (91.24) 56 (8.76)
 < 4.3 1136 (63.61) 1009 (65.99) 127 (11.18) 1041 (91.64) 95 (8.36)
 > 5.8 11 (0.62) 8 (72.73) 3 (27.27) 9 (81.82) 2 (18.18)
Monocyte count, × 10⁹/L 0.50 (0.40-0.63) 0.50 (0.40-0.62) 0.55 (0.46-0.70) <0.001 0.50 (0.40-0.63) 0.53 (0.41-0.70) <0.001
 0.1-0.6 1256 (70.32) 1102 (87.74) 154 (12.26) 1155 (91.96) 101 (8.04)
 < 0.1 6 (0.34) 5 (83.33) 1 (16.67) 6 (100.00) 0 (0)
 > 0.6 524 (29.34) 422 (80.53) 102 (19.47) 472 (90.08) 52 (9.92)
Hemoglobin, g/L 126 (115-137) 124 (114-135) 133 (123-144) <0.001 126 (115-137) 126 (116-140) 0.643
 130.0-175.0 712 (39.87) 565 (79.35) 147 (20.65) 650 (91.29) 62 (8.71)
 < 130.0 1069 (59.85) 961 (89.90) 108 (10.10) 979 (91.58) 90 (8.42)
 > 175.0 5 (0.28) 3 (60.00) 2 (20.00) 4 (80.00) 1 (20.00)
Platelet count, × 109/L 229.00 (187.00-277.25) 228 (186-276) 234.00 (192.50-287.00) 0.121 229.00 (187.50-277.00) 230.00 (170.50-288.50) <0.001
 125.0-350.0 1556 (87.12) 1340 (87.64) 216 (13.88) 1434 (92.16) 122 (7.84)
 < 125.0 77 (4.31) 60 (77.92) 17 (22.08) 60 (77.92) 17 (22.08)
 > 350.0 153 (8.57) 129 (8.44) 24 (15.69) 139 (90.85) 14 (9.15)
Albumin, g/L 37.70 (35.00-40.00) 37.60 (34.90-39.90) 38.30 (35.55-40.50) 0.109 37.80 (35.20-40.00) 36.90 (31.95-39.70) 0.380
 40-55 450 (25.17) 375 (83.33) 75 (16.67) 416 (92.44) 34 (7.560
 <40 1338 (74.83) 1156 (75.51) 182 (13.60) 1219 (91.11) 119 (8.89)
Total bilirubin, μmol/L 9.10 (7.00-12.00) 9.10 (6.90-11.90) 9.40 (7.20-12.95) 0.288 9.10 (7.00-11.90) 9.70 (6.85-13.90) 0.001
 5.0-21.0 1595 (89.20) 1367 (85.69) 228 (14.31) 1470 (92.16) 125 (7.84)
 < 5.0 124 (6.94) 109 (87.90) 15 (12.10) 110 (88.71) 14 (11.29)
 > 21.0 69 (3.86) 55 (79.71) 14 (20.29) 55 (79.71) 14 (20.29)
Creatinine, μmol/L 52.00 (36.00-75.00) 63.60 (54.00-76.00) 67.10 (57.70-78.10) 0.003 64.30 (54.70-76.50) 64.90 (52.30-72.45) 0.687
 64.0-104.0 814 (45.52) 672 (82.53) 142 (17.47) 743 (91.28) 71 (8.72)
 < 64.0 879 (49.16) 774 (88.04) 105 (11.96) 807 (91.81) 72 (8.19)
 > 104.0 93 (5.22) 83 (89.25) 10 (10.75) 83 (89.25) 10 (10.75)
Procalcitonin, ng/mL 0.04 (0.03-0.05) 0.04 (0.02-0.05) 0.05 (0.03-0.07) <0.001 0.04 (0.03-0.05) 0.06 (0.04-0.11) <0.001
 <0.05 1000 (65.96) 902 (90.20) 98 (9.80) 952 (95.20) 48 (4.80)
 >=0.05 516 (34.04) 394 (76.36) 122 (23.64) 425 (82.36) 91 (17.64)
Interleukin-6, pg/mL 1.50 (1.50-4.03) 1.50 (1.50-4.14) 1.5 (1.5-3.48) 0.695 1.50 (1.50-3.69) 2.72 (1.50-11.05) <0.001
 0-7.0 606 (83.59) 495 (83.33) 111 (84.73) 552 (91.09) 54 (8.91)
 >7.0 119 (16.41) 99 (83.19) 20 (16.81) 93 (78.15) 26 (21.85)
SARS-CoV-19 IgM 0.031 0.560
 NO 1569 (87.75) 1354 (86.30) 215 (13.70) 1437 (87.89) 132 (8.41)
 YES 219 (12.25) 177 (80.82) 42 (19.18) 198 (90.14) 21 (9.59)
SARS-CoV-19 IgG 0.44 0.303
 NO 1257 (70.30) 1090 (86.71) 167 (13.29) 1155 (81.89) 102 (8.11)
 YES 531 (29.70) 441 (83.05) 90 (16.95) 480 (90.40) 51 (9.60)