Table 2.
Covariate | All patientsMedian (IQR)/n (%) | ALT | AST | |||||
---|---|---|---|---|---|---|---|---|
Normal Median (IQR)/n (%) | Elevated Median (IQR)/n (%) | p-value | Normal Median (IQR)/n (%) | Elevated Median (IQR)/n (%) | p-value | |||
Leucocyte count, × 10⁹/L | 5.69 (4.70-6.90) | 5.63 (4.64-6.84) | 6.03 (5.03-7.32) | 0.009 | 5.68 (4.70-6.87) | 5.70 (4.81-7.11) | 0.084 | |
3.5-9.5 | 1592 (89.14) | 1362 (85.55) | 230 (14.45) | 1463 (91.90) | 129 (8.10) | |||
< 3.5 | 104 (5.82) | 97 (93.27) | 7 (6.370 | 93 (89.42) | 11 (10.58) | |||
> 9.5 | 90 (5.04) | 70 (77.78) | 20 (22.22) | 77 (85.56) | 13 (14.44) | |||
Neutrophil count, × 10⁹/L | 3.27 (2.53-4.25) | 3.24 (2.50-4.23) | 3.52 (2.77-4.52) | 0.001 | 3.25 (2.52-6.87) | 3.36 (2.61-4.54) | 0.012 | |
1.8-6.3 | 1558 (87.23) | 1336 (85.75) | 222 (14.25) | 1433 (91.98) | 125 (8.02) | |||
< 1.8 | 117 (6.55) | 109 (93.16) | 8 (6.84) | 107 (91.45) | 10 (8.55) | |||
> 6.3 | 111 (6.22) | 84 (75.68) | 27 (24.32) | 93 (83.78) | 18 (16.22) | |||
Lymphocyte count, × 10⁹/L | 1.60 (1.24-1.99) | 1.60 (.24-1.97) | 1.64 (1.21-2.04) | 0.130 | 1.62 (1.27-1.99) | 1.47 (0.95-1.94) | <0.001 | |
1.1-3.2 | 1462 (81.86) | 1259 (86.11) | 203 (13.89) | 1361 (93.09) | 101 (6.91) | |||
< 1.1 | 298 (16.69) | 251 (84.23) | 47 (15.77) | 247 (82.89) | 51 (17.11) | |||
> 3.2 | 26 (1.46) | 19 (73.08) | 7 (2.72) | 25 (1.53) | 1 (3.85) | |||
Erythrocyte count, × 1012/L | 4.12 (3.77-4.49) | 4.10 (3.73-4.44) | 4.32 (3.29-4.75) | <0.001 | 4.12 (13.77-4.49) | 4.12 (3.71-4.51) | 0.499 | |
4.3-5.8 | 639 (35.78) | 512 (80.13) | 127 (19.87) | 583 (91.24) | 56 (8.76) | |||
< 4.3 | 1136 (63.61) | 1009 (65.99) | 127 (11.18) | 1041 (91.64) | 95 (8.36) | |||
> 5.8 | 11 (0.62) | 8 (72.73) | 3 (27.27) | 9 (81.82) | 2 (18.18) | |||
Monocyte count, × 10⁹/L | 0.50 (0.40-0.63) | 0.50 (0.40-0.62) | 0.55 (0.46-0.70) | <0.001 | 0.50 (0.40-0.63) | 0.53 (0.41-0.70) | <0.001 | |
0.1-0.6 | 1256 (70.32) | 1102 (87.74) | 154 (12.26) | 1155 (91.96) | 101 (8.04) | |||
< 0.1 | 6 (0.34) | 5 (83.33) | 1 (16.67) | 6 (100.00) | 0 (0) | |||
> 0.6 | 524 (29.34) | 422 (80.53) | 102 (19.47) | 472 (90.08) | 52 (9.92) | |||
Hemoglobin, g/L | 126 (115-137) | 124 (114-135) | 133 (123-144) | <0.001 | 126 (115-137) | 126 (116-140) | 0.643 | |
130.0-175.0 | 712 (39.87) | 565 (79.35) | 147 (20.65) | 650 (91.29) | 62 (8.71) | |||
< 130.0 | 1069 (59.85) | 961 (89.90) | 108 (10.10) | 979 (91.58) | 90 (8.42) | |||
> 175.0 | 5 (0.28) | 3 (60.00) | 2 (20.00) | 4 (80.00) | 1 (20.00) | |||
Platelet count, × 109/L | 229.00 (187.00-277.25) | 228 (186-276) | 234.00 (192.50-287.00) | 0.121 | 229.00 (187.50-277.00) | 230.00 (170.50-288.50) | <0.001 | |
125.0-350.0 | 1556 (87.12) | 1340 (87.64) | 216 (13.88) | 1434 (92.16) | 122 (7.84) | |||
< 125.0 | 77 (4.31) | 60 (77.92) | 17 (22.08) | 60 (77.92) | 17 (22.08) | |||
> 350.0 | 153 (8.57) | 129 (8.44) | 24 (15.69) | 139 (90.85) | 14 (9.15) | |||
Albumin, g/L | 37.70 (35.00-40.00) | 37.60 (34.90-39.90) | 38.30 (35.55-40.50) | 0.109 | 37.80 (35.20-40.00) | 36.90 (31.95-39.70) | 0.380 | |
40-55 | 450 (25.17) | 375 (83.33) | 75 (16.67) | 416 (92.44) | 34 (7.560 | |||
<40 | 1338 (74.83) | 1156 (75.51) | 182 (13.60) | 1219 (91.11) | 119 (8.89) | |||
Total bilirubin, μmol/L | 9.10 (7.00-12.00) | 9.10 (6.90-11.90) | 9.40 (7.20-12.95) | 0.288 | 9.10 (7.00-11.90) | 9.70 (6.85-13.90) | 0.001 | |
5.0-21.0 | 1595 (89.20) | 1367 (85.69) | 228 (14.31) | 1470 (92.16) | 125 (7.84) | |||
< 5.0 | 124 (6.94) | 109 (87.90) | 15 (12.10) | 110 (88.71) | 14 (11.29) | |||
> 21.0 | 69 (3.86) | 55 (79.71) | 14 (20.29) | 55 (79.71) | 14 (20.29) | |||
Creatinine, μmol/L | 52.00 (36.00-75.00) | 63.60 (54.00-76.00) | 67.10 (57.70-78.10) | 0.003 | 64.30 (54.70-76.50) | 64.90 (52.30-72.45) | 0.687 | |
64.0-104.0 | 814 (45.52) | 672 (82.53) | 142 (17.47) | 743 (91.28) | 71 (8.72) | |||
< 64.0 | 879 (49.16) | 774 (88.04) | 105 (11.96) | 807 (91.81) | 72 (8.19) | |||
> 104.0 | 93 (5.22) | 83 (89.25) | 10 (10.75) | 83 (89.25) | 10 (10.75) | |||
Procalcitonin, ng/mL | 0.04 (0.03-0.05) | 0.04 (0.02-0.05) | 0.05 (0.03-0.07) | <0.001 | 0.04 (0.03-0.05) | 0.06 (0.04-0.11) | <0.001 | |
<0.05 | 1000 (65.96) | 902 (90.20) | 98 (9.80) | 952 (95.20) | 48 (4.80) | |||
>=0.05 | 516 (34.04) | 394 (76.36) | 122 (23.64) | 425 (82.36) | 91 (17.64) | |||
Interleukin-6, pg/mL | 1.50 (1.50-4.03) | 1.50 (1.50-4.14) | 1.5 (1.5-3.48) | 0.695 | 1.50 (1.50-3.69) | 2.72 (1.50-11.05) | <0.001 | |
0-7.0 | 606 (83.59) | 495 (83.33) | 111 (84.73) | 552 (91.09) | 54 (8.91) | |||
>7.0 | 119 (16.41) | 99 (83.19) | 20 (16.81) | 93 (78.15) | 26 (21.85) | |||
SARS-CoV-19 IgM | 0.031 | 0.560 | ||||||
NO | 1569 (87.75) | 1354 (86.30) | 215 (13.70) | 1437 (87.89) | 132 (8.41) | |||
YES | 219 (12.25) | 177 (80.82) | 42 (19.18) | 198 (90.14) | 21 (9.59) | |||
SARS-CoV-19 IgG | 0.44 | 0.303 | ||||||
NO | 1257 (70.30) | 1090 (86.71) | 167 (13.29) | 1155 (81.89) | 102 (8.11) | |||
YES | 531 (29.70) | 441 (83.05) | 90 (16.95) | 480 (90.40) | 51 (9.60) |