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. 2021 Nov 16;8:751637. doi: 10.3389/fmolb.2021.751637

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Copyright © 2021 Loaeza-Reyes, Zenteno, Moreno-Rodríguez, Torres-Rosas, Argueta-Figueroa, Salinas-Marín, Castillo-Real, Pina-Canseco and Cervera.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Core structures reported of mucin-type O-glycans, eight in total, only cores 1–4 show widespread abundance, core structures 5–8 have a highly restricted occurrence, and core 7 has not been found in humans. (B) ApoC-III present in LDL, VLDL, and HDL is glycosylated in the Golgi apparatus, apoCIII₀ (non-sialylated) is associated with proatherogenic profile lipids; apoCIII₁ (mono-sialylated) and apoCIII₂ (di-sialylated) are inversely associated with proatherogenic profile lipids.