Fig. 4. Study of the glycosidic bond cleavage from the glycosylated platinum(ii) complex. (a) TEM images of the as-assembled structures of 1a at different pH and/or with β-glu (0.5 U mL⁻¹) after 24 h. (b) UPLC/MS analysis of 1a in different media for 24 h. (i) 1a in PBS (pH 7.4), (ii) 1d in PBS (pH 7.4), (iii) 1a in PBS (pH 5.8) and (iv) 1a with β-glu (0.5 U mL⁻¹) in PBS (pH 5.8). (c) Time-dependent release of 1d in the absence or presence of β-glu. (d) Schematic illustration of the β-glucosidase-mediated cleavage of glucose in 1a.