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. 2021 Nov 16;12:752129. doi: 10.3389/fgene.2021.752129

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Copyright © 2021 Sheng, Guo, Zhang, Zhang, Miao, Tan, Hu, Li, Ding, Li and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional interaction network and a diagrammatic mode illustrate the regulatory mechanism of the MSTN gene on the focal adhesion, PI3K-AKT, and ribosomal pathways. (A) MSTN, FAK, AKT1, RPS6, and 55 Differentially expressed proteins were submitted to conduct blast searching against the existing databases in STRING 11 software. (B) “→” The activation of the process, “ -| ” the inhibition of the process, “– –” the presence of intermediate steps either unknown or omitted. Up-regulated differentially expressed proteins were marked with red font, while down-regulated differentially expressed proteins were marked with blue font.