Skip to main content
. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Nat Chem Biol. 2021 May 25;17(6):693–702. doi: 10.1038/s41589-021-00801-x

Extended Data Figure 3. Droplet rate increases rapidly relative to bulk as a function of partition coefficient.

Extended Data Figure 3.

(A) Modeled ratio of droplet and bulk reaction rates as a function of substrate concentration and partition coefficient (PC). Both reactions are scaffolded and have KM = 17. Enzyme partitioning is identical to substrate partitioning, and [E] = 0.1[S].

(B) Modeled fractional activity contributed by the droplet phase as a function of substrate concentration and partition coefficient (PC). Conditions same as in (A), with a 0.01 droplet volume fraction.