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. 2021 Dec 1;7(49):eabl8213. doi: 10.1126/sciadv.abl8213

Fig. 4. Clinical adenoviruses bind to PF4 with nanomolar affinity.

Fig. 4.

Single-injection SPR experiments show that ChAdOx1 (A), HAdV-C5 (B), and HAdV-D26 (C) form stable and reproducible interactions with PF4. Affinity was calculated using the steady state model (D), and the curve showed close fit to the tested concentrations (insets).