Fig. 3. PCL induces B cell antigen presentation in the quad tissue.

(A) Flow cytometry counts of B cell subsets: CD19⁺B220⁻, CD19⁻B220⁺, and CD19⁺B220⁺ in the quad tissue at day 5 after injury. (B) MHCII⁺B220⁺ cell population in quadricep tissue at day 5 after injury. (C) Flow cytometry counts of B cell subsets: CD19⁺B220⁻, CD19⁻B220⁺, and CD19⁺B220⁺ in the quad tissue at week 3 after injury. Data from CD19⁻B220⁺ are also used in Fig. 1A. Data are means ± SD, n = 4, two-way ANOVA with subsequent multiple comparison testing [(B and C): *P < 0.05, **P < 0.01]. VML indicates injury with saline, ECM indicates injury with ECM, and PCL indicates injury with PCL.