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. 2021 Dec;2(12):e811–e819. doi: 10.1016/S2666-7568(21)00253-1

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© 2021 Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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RBD and neutralising antibody titres by previous infection status

(A) RBD titre to England.2 strain at T1 and T2 for all individuals with detectable RBD antibodies at T1. (B) Live virus neutralising antibody titre to England.2 virus at T1 and T2 for all individuals with detectable RBD antibodies at T1. Bars indicate geometric mean and 95% CI. Dashed line indicates assay threshold. Timepoint T1 was May, June, or July, 2020, 4 weeks after the first set of testing. Timepoint T2 was September or October, 2020, 4 months after baseline T1 serology. RBD=receptor binding domain assay. Statistical analysis using Wilcoxon matched pairs: *p<0·0001, † p=0·039. ‡p<0·0001, §p<0·0039.