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. 2021 Dec 1;4(2):e135–e144. doi: 10.1016/S2665-9913(21)00322-2

Figure 2.

Figure 2

Optimal trajectory of COVID-19 pneumonia

Typically, SARS-CoV-2 alveolar infection proceeds with a viral phase, an inflammatory phase, and an associated immunothrombotic phase. In severe disease, ARDS can develop. In patients who are otherwise immunocompetent, obesity and other cardiovascular risk factors can lead to cardiopulmonary system decompensation. ARDS=acute respiratory distress syndrome.