Table 2.
Association of UMOD SNPs with longitudinal blood pressure changes changes blood pressure from baseline to the follow-ups.
| SNP | BP(2004–2009) | BP(2004–2012) | ||||||
|---|---|---|---|---|---|---|---|---|
| SBP change | DBP change | MAP change | PP change | SBP change | DBP change | MAP change | PP change | |
| rs4632135 | 0.487 | 0.885 | 0.665 | 0.394 | 1.000 | 0.649 | 0.788 | 0.722 |
| rs4383153 | 0.487 | 0.885 | 0.665 | 0.394 | 1.000 | 0.649 | 0.788 | 0.722 |
| rs11859916 | 0.110 | 0.349 | 0.178 | 0.140 | 0.160 | 0.430 | 0.240 | 0.041a |
| rs7198000 | 0.162 | 0.421 | 0.242 | 0.195 | 0.352 | 0.533 | 0.402 | 0.452 |
| rs7193058 | 0.186 | 0.431 | 0.262 | 0.227 | 0.094 | 0.274 | 0.136 | 0.171 |
| rs77875418 | 0.577 | 0.427 | 0.459 | 0.889 | 0.217 | 0.300 | 0.218 | 0.407 |
| rs79245268 | 0.538 | 0.412 | 0.433 | 0.841 | 0.120 | 0.224 | 0.133 | 0.264 |
| rs4293393 | 0.562 | 0.430 | 0.454 | 0.861 | 0.112 | 0.134 | 0.092 | 0.344 |
| rs6497476 | 0.538 | 0.412 | 0.433 | 0.841 | 0.120 | 0.224 | 0.133 | 0.264 |
| rs4997081 | 0.745 | 0.730 | 0.716 | 0.860 | 0.378 | 0.341 | 0.314 | 0.667 |
| rs13333226 | 0.516 | 0.388 | 0.408 | 0.833 | 0.087 | 0.100 | 0.066 | 0.320 |
| rs12708631 | 0.012b | 0.006 b | 0.004b | 0.166 | 0.030a | 0.020b | 0.020 | 0.236 |
| rs12917707 | 0.009 | 0.600 | 0.107 | 0.001 | 0.023b | 0.726 | 0.403 | 0.002 |
For associations that were not significant under any model, P values for an additive model are listed. All genetic models are based on the minor allele of each SNP. BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure. MAP, mean arterial pressure; PP, pulse pressure; OR, odds ratio; SNP, single nucleotide polymorphism.
Dominant model.
Recessive model.
Statistically values are presented in bold.