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. 2021 Nov 17;8:744788. doi: 10.3389/fcvm.2021.744788

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Copyright © 2021 Mehta, Wei, Shufelt, Quesada, Shaw and Bairey Merz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Calibration plots of risk score-specific predicted vs. observed rate of events. Commonly used cardiovascular risk scores significantly underestimate risk in women with ischemia and no obstructive CAD. Dotted line is the reference line for equal predicted and observed risk. Solid line is the observed risk. ASCVD, Atherosclerotic Cardiovascular Disease risk score; ATP III-FRS, Adult Treatment Panel III risk score; FRS, Framingham Risk Score; QRISK2, cardiovascular risk score; RRS, Reynolds Risk Score; and SCORE, Systematic Coronary Risk Evaluation. Reprinted with permission (66).