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. 2021 Nov 17;8:789931. doi: 10.3389/fcvm.2021.789931

Figure 1.

Figure 1

Mechanism of non-statin drugs (ezetimibe, PCSK9 inhibitors, bempedoic acid, and inclisiran). CoA, coenzyme A; ATP-CL, ATP citrate lyase; HMG-CR, HMG-CoA reductase; NPC1L1, Niemann-Pick C1-Like 1; mRNA, messenger RNA.