TABLE 1.

New approaches that target cholesterol metabolism in HCC.

Drugs	Target	Clinical development	Effects	References
Statins	HMGCR	In phase II clinical trials	Controversial	70–79
Ezetimibe	NPC1L1	In preclinical development	Suppressed development of liver tumor	69, 80
Terbinafine	SQLE	In preclinical development	Attenuated HCC in cell and mice model	43, 46