Table 2.
Comparison of IVGTT-based indices among three groups.
| Variables | G1 (n = 21) | G2 (n = 95) | G3 (n = 10) | p for linear trend |
|---|---|---|---|---|
| AUCGlu | 137.07 ± 24.97 | 144.79 ± 20.87 | 151.44 ± 36.16 | 0.107 |
| AUCIns | 787.40 (581.80,1077.00) | 891.70 (592.90,1345.00) b | 389.00 (221.10,562.10) c | 0.038 |
| AUCC-p | 43.61 (34.27,51.14) | 47.15 (36.51,66.38) b | 23.21 (20.96,43.92) | 0.096 |
| AUCIns/AUCGlu | 5.73 (4.30,7.58) | 6.00 (3.76,10.49) b | 2.65 (1.20,4.18) c | 0.023 |
| △Ins3/△Glu3 | 8.00 (6.48,13.93) | 9.21 (6.17,14.13) b | 3.44 (1.35, 5.71) c | 0.002 |
| △Ins10/△Glu10 | 6.76 (5.08,9.51) | 6.23 (3.70,10.65) b | 1.85 (1.34,5.88) c | 0.025 |
Data are presented as mean ± SD or as median (interquartile range).
AUC, area under curve; Glu, plasma glucose; Ins, insulin; C-p, C-peptide; △Insy/△Gluy = (Insy − Ins0)/(Gluy − Glu0), Insy and Gluy represented insulin and glucose values, respectively, at time y min during the intravenous glucose tolerance test.
a
Difference between group 1 and group 2 was statistically significant(p1–2 < 0.05).
b
Difference between group 2 and group 3 was statistically significant (p2–3 < 0.05).
c
Difference between group 1 and group 3 was statistically significant (p1–3 < 0.05).
P values < 0.05 were shown in bold.