Table 2.

Sample size calculations

Treatment	Per cent leading to a scale 1–2	Sample size
SOC	60	32
SOC+E2+P4	90	32
SOC	60	22
SOC+E2+P4	95	22
SOC	70	62
SOC+E2+P4	90	62
SOC	70	36
SOC+E2+P4	95	36

E2, oestradiol cypionate; P4, micronised progesterone; SOC, standard of care.