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. 2021 Nov 24;2021:4468625. doi: 10.1155/2021/4468625

Figure 5.

Figure 5

Chemerin aggravated HG-induced inflammatory responses in ARPE-19 cells. ARPE-19 cells were exposed to 10 nM recombinant human chemerin or (and) 30 mM HG for 24 h, and then ELISA was used to measure the concentrations of IL-1β (a), TNF-α (b), and IL-6 (c) in cell supernatants. N = 6 for each group. RT-qPCR was used to measure the mRNA levels of IL-1β (d), TNF-α (e), and IL-6 (f) from cells. N = 3 for each group. ##p < 0.01 and ###p < 0.001 compared to control, @p < 0.05 and @@@p < 0.001 compared to HG group. One-way ANOVA followed by Dunnett's T3 multiple comparisons test.