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Chemerin aggravated HG-induced VEGF activation in ARPE-19 cells. ARPE-19 cells were exposed to 10 nM recombinant human chemerin or (and) 30 mM HG for 24 h RT-qPCR was used to measure the mRNA levels of VEGF (a) and western blot was used to measure the protein levels of VEGF ((b) and (c)). N = 3 for each group. #p < 0.05 and ##p < 0.01 compared to control; @@p < 0.01 and @@@p < 0.001 compared to HG group. One-way ANOVA followed by Dunnett's T3 multiple comparisons test.
