Table 2.

Baseline information of exposures used in our analyses.

Exposure		Outcome		Number of IVs		R 2		Power (%)		F_statistics
Trait	Sample	Trait	Sample	mvMR	uvMR	mvMR	uvMR	mvMR	uvMR	mvMR	uvMR
FEV1	79,055	AF	1,030,836		9		0.0059		4		467.76
FVC	79,055	AF	1,030,836	28	8	0.0198	0.0045	100	2	1596.87	355.65
FEV1/FVC	79,055	AF	1,030,836		16		0.0125		38		991.84
AF	1,030,836	FEV1	79,055	–	82	–	0.1866	–	100	–	163,697.38
AF	1,030,836	FVC	79,055	–	82	–	0.1866	–	100	–	163,697.38
AF	1,030,836	FEV1/FVC	79,055	–	82	–	0.1866	–	100	–	163,697.38

FEV1, forced expiratory volume in one second; FVC, forced vital capacity; FEV1/FVC, the ratio of FEV1 over FVC; AF, atrial fibrillation; IVs, instrumental variables; R², Variance explained by the SNPs on exposure.