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. 2021 Nov 16;12:729952. doi: 10.3389/fmicb.2021.729952

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Copyright © 2021 Zhang, Guo, Li, Li, Yang, Ni, Zhan, Lu, Zhang, Li and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Details of variants of bla_NDM genes, replicon types of plasmids, and the conjugative transfer modules of the 114 bla_NDM-positive plasmids in E. coli. The five categories of information present in this figure include the phylogenetic tree of 114 bla_NDM-positive plasmids, variants of bla_NDM genes, replicon types, conjugative transfer modules, and STs of host strains. The gradient of color of each heatmap (variants of bla_NDM genes, replicon types, phylogenetic patterns, conjugative transfer modules including oriT, relaxase, T4CP, and T4SS) represents the variable numbers of genes or gene clusters.