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. 2021 Nov 12;12:747536. doi: 10.3389/fneur.2021.747536

Table 5.

Associations of imaging variables with subcortical vascular dementia, N = 57.

Dementia
OR (95%CI) p
MARS
Infratentorial 1.00 (0.93–1.07) 0.963
Deep 1.03 (0.99–1.08) 0.161
Lobar 1.00 (0.99–1.02) 0.739
Total 1.00 (0.99–1.01) 0.580
ARWMC
Infratentorial 0.53 (0.10–2.80) 0.458
Basal ganglia 1.67 (0.74–3.78) 0.221
Subcortical 2.03 (1.24–3.32) 0.005*
Total 1.43 (1.09–1.89) 0.011*
PVSE
Centrum semiovale 0.72 (0.36–1.42) 0.339
Basal ganglia 1.10 (0.44–2.74) 0.837
Lesion quantity
ICH 1.00 (0.75–1.34) 1.000
Lacune 1.18 (1.02–1.35) 0.023*
Lesion burden score
CAA-SVD score 2.33 (1.01–5.40) 0.047*
C1 1.41 (1.09–1.83) 0.009*
C2 1.38 (1.08–1.76) 0.010*

ICH, intracerebral hemorrhage; MARS, Microbleed anatomical rating scale; ARWMC, Age-related White Matter Change; PVSE, enlargement of the perivascular space; CAA, cerebral amyloid angiopathy; SVD, small vessel disease; OR, odd's ratio.

ORs determined by multivariate logistic regression, adjusted for age, sex, and CCI;

*

p < 0.05.

Sum of total MARS score and total ARWMC scale.

Sum of total MARS score, total ARWMC scale, BG PVSE (≥20), and lacune (≥5).