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. 2021 Nov 15;13:770528. doi: 10.3389/fnagi.2021.770528

TABLE 1.

Demographic characteristics and scores of clinical assessments.

HC (n = 46) PD-NC (n = 47) PD-MCI (n = 45) P
Age 61.936.51 62.1710.27 63.119.39 0.80
Sex (M/F) 24/22 26/21 24/21 0.95
Education (years) 10.783.48 10.533.49 10.043.50 0.87
Disease duration (years) N/A 3.552.48 3.762.33 0.57
UPDRS-III N/A 28.6411.19 31.3610.41 0.25
H-Y stage N/A 1.660.72 1.890.82 0.20
LEED N/A 430.68146.75 454.04151.62 0.46
MoCA 28.201.19 27.641.49 21.162.28a,b <0.001
HVLT-R (total) 21.873.99 20.774.26 18.623.58a,b <0.001
HVLT-R (delayed) 7.802.21 7.152.48 6.512.42a <0.001
HVLT-R (recognition) 8.672.16 8.262.26 7.732.03 0.12
SDMT 46.0411.61 42.4311.86 37.6713.08a 0.006
TMT-A 62.2015.61 68.0619.34 76.1117.57a,b 0.001
TMT-B 123.4331.43 137.9633.79 155.0243.30a,b <0.001
BNT 24.723.23 23.173.61 18.985.17a,b <0.001
JoLO 22.634.93 21.025.43 17.025.14a,b <0.001

Data were represented as mean ± SD; N/A indicates not applicable. aIndicates significant difference to the HC group. bIndicates significant difference to the PD-NC group.

HC, healthy control; PD, Parkinson’s disease; NC, normal cognition; MCI, mild cognitive impairment; M, male; F, female; UPDRS, Unified Parkinson’s Disease Rating Scale; H-Y, Hoehn–Yahr; LEED, levodopa equivalent daily dose; MoCA, Montreal Cognitive Assessment; HVLT, Hopkins Verbal Learning Test-Revised; SDMT, Symbol Digit Modalities Test; TMT, Trail Making Test; BNT, Boston Naming Test; JoLO, Benton’s Judgment of Line Orientation.