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. 2021 Nov 12;8:731261. doi: 10.3389/fcvm.2021.731261

Table 3.

CAR level and risk of all-cause death of CTO-PCI patients, stratified by various baseline characteristics.

Characteristics CAR-L CAR-M CAR-H Interaction P-Value
Age
<65 y 1 (Reference) 1.31 (0.35-4.89), p = 0.687 1.87 (0.55–6.41), p = 0.317 0.244
≥65 y 1 (Reference) 1.03 (0.42–2.54), p = 0.950 3.40 (1.58–7.28), p = 0.002
Sex
Male 1 (Reference) 1.28 (0.57–2.89), p = 0.545 2.86 (1.42–5.77), p = 0.003 0.608
Female 1 (Reference) 0.83 (0.12–5.90), p = 0.853 4.25 (0.88–20.63), p = 0.072
Smoking
Yes 1 (Reference) 1.35 (0.53–3.44), p = 0.524 2.43 (1.03–5.76), p = 0.044 0.417
No 1 (Reference) 0.88 (0.25–3.03), p = 0.835 3.70 (1.39–9.87), p = 0.009
Diabetes mellitus
Yes 1 (Reference) 0.89 (0.29–2.78), p = 0.843 1.92 (0.74–4.99), p = 0.183 0.466
No 1 (Reference) 1.52 (0.54–4.28), p = 0.431 4.46 (1.79–11.10), p = 0.001
Hypertension
Yes 1 (Reference) 1.53 (0.56–4.16), p = 0.409 2.53 (1.04–6.17), p = 0.042 0.388
No 1 (Reference) 0.91 (0.29–2.82), p = 0.871 3.40 (1.36–8.52), p = 0.009
LDL
≥2.46 mmol/l 1 (Reference) 1.09 (0.26–4.53), p = 0.903 1.98 (0.59–6.59), p = 0.266 0.074
<2.46 mmol/l 1 (Reference) 1.09 (0.42–2.83), p = 0.859 3.88 (1.74–8.63), p = 0.001
HDL
>1.04 mmol/l 1 (Reference) 0.69 (0.17–2.91), p = 0.616 2.42 (0.81–7.24), p = 0.115 0.942
< =1.04 mmol/l 1 (Reference) 1.14 (0.45–2.90), p = 0.780 3.07 (1.37–6.88), p = 0.006
TG
≥1.68 mmol/l 1 (Reference) 0.87 (0.23–3.25), p = 0.837 1.44 (0.47–4.42), p = 0.522 0.116
<1.68 mmol/l 1 (Reference) 1.06 (0.41–2.77), p = 0.902 3.92 (1.73–8.91), p = 0.001

CAR, C-reactive protein to albumin ratio; BMI, body mass index; MI, myocardial infarction; DBP, diastolic blood pressure; SBP, systolic blood pressure; LDL, Low-density lipoprotein; HDL, High-density lipoprotein; hsCRP, high sensitivity C-reactive protein; LVEF, left ventricular ejection fraction; CK-MB, creatine kinase isoenzymes MB; pro-BNP, pro-B-type natriuretic peptide; TSH, thyroid stimulating hormone; ACEI, angiotensin-converting enzyme inhibition; ARB, angiotensin receptor blocker.