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. 2021 Nov 16;9:780461. doi: 10.3389/fcell.2021.780461

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Copyright © 2021 Lin, Wang, Wang, Shao, Yang, Cao, Feng, Gao and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of prognostic cellular senescence-related DEGs. (A). Volcano plot of cellular senescence-related genes in TCGA database; red and green nodes indicate upregulated and downregulated genes, respectively. (B). Venn diagram showing 10 overlapping genes in DEGs and prognostic genes. (C). Forrest plot of the univariate Cox analysis of 10 overlapping genes. (D). Correlation network of 10 candidate genes. (E). LASSO coefficient profiles of 10 candidate genes. (F). Cross-validation for tuning parameter selection in the LASSO regression.