Figure 7.

CCND3 overexpression partially rescues cancer cell phenotypes in METTL1/WDR4-depleted A549 cells

(A) Validation of the CCND3 overexpression in METTL1-depleted A549 cells. (B and C) Overexpression of CCND3 partially rescued the growth (B) and invasion capacity (C) of METTL1-depleted A549 cells. (D) Validation of the CCND3 overexpression in WDR4-depleted A549 cells. (E and F) Overexpression of CCND3 partially rescued the growth (E) and invasion capacity (F) of WDR4-depleted A549 cells. Data were presented as mean ± SD. Scale bar, 200 μm. (One-way ANOVA, two-way ANOVA, ∗p < 0.05, ∗∗∗p < 0.001.)