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. 2021 Sep 23;56(12):3049–3058. doi: 10.1038/s41409-021-01452-1

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© The Author(s) 2021

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Fig. 2 — Flow cytometry assays of the different organs at different time points after treatment were performed. A Percentage of effector (T_EF/EM:CD44⁺⁺CD62L⁻) T cells were analyzed. B Percentage of CD8⁺ (SP), CD4⁺ (SP), CD4⁺ CD8⁺ (DP) and CD4⁻CD8⁻ (DP) in the thymus. Data are shown as mean ± SEM. Data are collected from 4–5 independent experiments with 5–6 mice per group. *P < .05, **P < .01, and ***P < .001. UTM: untreated transplanted mice (vehicle administration); IXZ: ixazomib group; HD: healthy donor; SYG: syngeneic group; 2/4 and +10 W: weeks after starting the treatment. P values were calculated using 1-way ANOVA and 2-sided Student’s unpaired t-test.