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PNA telo-FISH to testis suspension nuclei of Atm-p53-deficient mice. (a and b) Telomeres (whitish) are scattered throughout premeiotic, somatic nuclei (gray), as seen at the maximum nuclear diameter. (c and d) Top view of spermatocyte I nuclei which display telomeres clustered at a limited sector of the nuclear periphery (indicative of leptotene-zygotene transition). DNA was counterstained with DAPI (gray).
