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. 2021 Dec 1;11:23246. doi: 10.1038/s41598-021-02681-6

Figure 6.

Figure 6

MPA inhibits the upregulation of HBD2 by polarized endometrial epithelial cells following injury. Secretion of (A) HBD2, (B) CCL20, (C) RANTES, and (D) SDF-1α by endometrial epithelial cells grown in transwell inserts 48 h post-scratch. Cells were treated for 48 h with 100 nM MPA, NET, and LNG prior to scratch and maintained in cell culture media following scratch. Bars represent mean + /− SEM. Secretion values were normalized to the control wells which were set to 100. Each symbol represents a single individual (Control n = 8; MPA n = 8; NET n = 4; LNG; n = 4). Mean secretion in controls samples: 850 pg/ml (HBD2), 575 pg/ml (CCL20), 37 pg/ml (RANTES), and 59 pg/ml (SDF-1α). Control untreated unscratched control, Control + SC scratched control, MPA unscratched MPA treated, MPA + SC scratched MPA treated, NET unscratched NET treated, NET + SC scratched NET treated, LNG unscratched LNG treated, LNG + SC scratched LNG treated. *p < 0.05.