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. 2021 Dec 1;12:7002. doi: 10.1038/s41467-021-27125-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Heatmap of MNase signal in Ctrl and DomKD embryos at ZGA in Zld-dependent, H2A.Z positive and H2A.Z negative promoters. The heatmap is sorted by MNase-seq signal in Ctrl embryos. Tracks show the signal obtained after merging two biological replicates per condition. b Profile plots of insulation score in Zld-dependent, H2A.Z positive and H2A.Z negative promoters comparing Ctrl vs DomKD embryos at ZGA. The center line indicates the median and the semi-transparent lines represent the standard error of a given group and condition, which indicates that in all groups DomKD is significantly different than the control at TSS. c Heatmap of the insulation score in Ctrl and DomKD embryos sorted by H2A.Z Ctrl signal at ZGA. All tracks are from embryos at ZGA.