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. 2021 Dec 1;8:39. doi: 10.1186/s40580-021-00287-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 11 — a Representative fluorescence images showing nanocup penetration to a tissue model hydrogel after ultrasound treatment.

Adapted from reference [37], Copyright 2015, John Wiley and Sons. b Phospholipid stabilized hydrophobic MSN penetration to agarose gel due to the generated cavitation events. Nanoparticles were labeled with fluorescein for imaging. Adapted from reference [46], Copyright 2018, American Chemical Society