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. 2021 Dec;219(6):686–694. doi: 10.1192/bjp.2021.142

Table 6.

Syndemics PLS-SEM for total sample showing combination of the direct, indirect and total effects

Structural comparison Direct effects, s.c. Indirect effects, s.c. Total effects, s.c.
Past adversity → current adversity 0.178 0.016 0.194
Past adversity → biomarkers 0.007 0.041 0.047
Past adversity → psychosis 0.028 0.009 0.037
Current adversity → past adversity 0.187 0.017 0.205
Current adversity → biomarkers 0.227 0.020 0.247
Current adversity → psychosis 0.038 0.013 0.050
Biomarkers → past adversity 0.007 0.042 0.048
Biomarkers → current adversity 0.219 0.019 0.239
Biomarkers → psychosis 0.019 0.011 0.029

PLS-SEM, partial least squares structural equation model; s.c., standardised coefficient; arrows indicate directions of associated tested.