Table 1.
Demographics, symptoms, signs and lab results by diagnostic group (for cloazpine administered instances)
| Myocarditis confirmed (n = 27) | Myocarditis ruled out (n = 191) | Myocarditis undetermined (n = 23) | |
|---|---|---|---|
| Demographic characteristics | |||
| Gender, n (%) male | 23 (85.2) | 137 (71.7) | 15 (65.2) |
| Ethnicity, % | |||
| White | 12 (44.4) | 37.9 | 10 (43.5) |
| Black | 12 (44.4) | 47.9 | 11 (47.8) |
| Other | 3 (11.1) | 14.2 | 2 (8.7) |
| Age, years: mean (%) | 36.87 (13.55) | 38.0 (12.54) | 35.13 (13.37) |
| Age bands, years: n (%) | |||
| 0–29 | 11 (40.7) | 63 (33.0) | 10 (43.5) |
| 30–39 | 4 (14.8) | 45 (23.6) | 7 (30.4) |
| 40–49 | 6 (22.2) | 49 (25.7) | 3 (13.0) |
| 50–80 | 6 (22.2) | 34 (17.8) | 3 (13.0) |
| Clinical characteristics | |||
| Symptoms, n (%) | |||
| Chest pain | 12 (44.4) | 34 (18.4) | 6 (40.0) |
| Malaise | 13 (56.5) | 39 (21.4) | 8 (57.1) |
| SOB | 8 (34.8) | 27 (14.6) | 1 (7.1) |
| Oedema | 0 (0.0) | 1 (0.5) | 0 (0.0) |
| Palpitations | 1 (4.5) | 8 (4.3) | 2 (14.3) |
| Vital signsa | |||
| Mean temperature, mean (s.d.) | 37.96 (1.12) | 37.49 (1.01) | 38.10 (1.61) |
| Abnormal temperature, n (%) | 13 (59.1) | 59 (44.7) | 5 (62.5) |
| Mean blood pressure, mean (s.d.) | 115.3/70.2 (19.0/14.1) | 126.1/82.2 (18.4/11.4) | 131.6/85.3 (27.6/13.8) |
| Abnormal blood pressure, n (%) | 6 (30.0) | 37 (25.9) | 3 (30.0) |
| Mean % saturation, mean (s.d.) | 96.50 (1.87) | 97.56 (5.43) | 95.67 (5.82) |
| Abnormal saturation, n (%) | 1 (7.1) | 8 (7.8) | 1 (16.7) |
| Mean pulse rate, mean (s.d.) | 116.30 (11.86) | 112.25 (14.30) | 114.67 (12.85) |
| Abnormal pulse rate, n (%) | 23 (100.0) | 156 (89.7) | 12 (100.0) |
| Labb | |||
| Mean CRP, mean (s.d.) | 87.39 (64.27) | 18.80 (27.89) | 86.76 (62.41) |
| Abnormal CRP (>5 mg/L), n (%) | 18 (100.0) | 68 (53.1) | 5 (55.6) |
| Mean CK, mean (s.d.) | 169.92 (112.50) | 575.98 (1779.46) | 167.57 (193.36) |
| Abnormal CK (>150 Units/L), n (%) | 7 (58.3) | 50 (60.2) | 1 (14.3) |
| Mean troponin mg/L, mean (s.d.) | 1926.54 (4501.22) | 18.33 (69.18) | 121.42 (212.21) |
| Abnormal troponin (>16 ng/L), n (%) | 24 (100.0) | 14 (10.4) | 11 (91.7) |
| Mean WBC, mean (s.d.) | 9.36 (2.63) | 8.42 (3.51) | 11.58 (4.03) |
| Abnormal WBC (>11 × 109/L), n (%) | 6 (28.6) | 25 (18.4) | 5 (55.6) |
| Mean eosinophils, mean (s.d.) | 0.87 (1.37) | 0.37 (0.85) | 0.28 (0.14) |
| Abnormal eosinophils (>0.4× 109/L), n (%) | 10 (62.5) | 16 (13.6) | 1 (16.7) |
| Any ECG anomalies, n (%) | 10 (47.6) | 26 (15.7) | 3 (23.1) |
SOB, Shortness Of Breath. CRP, C-reactive protein; CK, creatine kinase; WBC, white blood count; ECG, electrocardiogram.
a. At the time of first suspicion.
b. First measure to be taken upon raising the suspicion, or as triggers for suspicion.