Fig. 7. Mechanism of Rad26-assisted Pol II forward translocation on a damaged DNA template.
The RecA1 and RecA2 domains are shown in dark and light green, CTD and the insertion helices are shown in purple, Pol II in gray, the DNA strands in light and dark blue. The directions of the swing motions of the ATPase domains and the rotation of the upstream DNA duplex are depicted by dashed arrows. The red star indicates the ATP hydrolysis event.