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Filter criteria for hotspot mutation profiling.
| Category/group | In vitro | Immunodeficient | Immunocompetent | Immunotherapy | |
|---|---|---|---|---|---|
| Nude | C57BL/6 J | αPD-L1 | αPD-1 | ||
| Category 1:PD-1 dependent immune suppressor candidates | Negative | Negative | Positive in at least two of these tumors | Negative | |
| Category 2:Non-PD-1 immune suppressor candidates | Negative | Negative | Positive in at least two of these tumors | Positive in any tumor | |
(Positive, AF ≥ 0.1; Negative, AF < 0.1)
