Fig. 3.
Recapitulation of the pathological features of scar. (A, B) (A)The differential expression profile of normal dECM and scar dECM and (B) GO analysis of differentiated proteins. (C) The printed groups with different bioinks. (D, E) The expression of myofibroblast markers at gene (D) (Data are mean ± SEM, n = 3, *p < 0.05) and protein (E) level (α-SMA, TGFβ1, Col I: red, DAPI: blue, scale bar = 25 μm). (F) Transcriptional analysis of scar model with different combination of environmental cues and scar tissue. 1ASS: 1A3G+SFb+scar ECM, 3AS: 3A5G+SFb, 3ASS: 3A5G+SFb+scar ECM, SFt: scar tissue. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
