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. 2021 Nov 16;15:774569. doi: 10.3389/fncel.2021.774569

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Copyright © 2021 Li, Zhang, Jia, Yang, Zhang, Zhang, Li, Jin, Wang, Tao, Chen, Liang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Electroacupuncture intervention could promote the expression of aerobic glycolysis (AG)-related proteins. (A–D) The expression of AMPK, 2,6-fructose-biphosphatase 3 (PFKFB3), hexokinase II (HK2), and pyruvate kinase M2 (PKM2) in the hippocampus of five groups after EA intervention; (E) representative protein images of each AG-related protein in different groups. *P < 0.05, **P < 0.01 vs. the WT group; ^#P < 0.05 vs. the AD group; ^∧P < 0.05; ^∧∧P < 0.01 vs. the AD + AMPK^(+/–) group; ^&P < 0.05 vs. the AD + EA group.