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. 2021 Sep 23;10:222–235. doi: 10.1016/j.bioactmat.2021.09.003

Fig. 10.

Fig. 10

ICP-MS analysis of the cell culture medium after 24 h of cell experiment on all β-TCP cylinders (CaP1: Ca/P = 1.496, CaP2: Ca/P = 1.497, CaP3: Ca/P = 1.497, CaP4: Ca/P = 1.498, CaP5: Ca/P = 1.500 and CaP6: Ca/P = 1.502) in contact with cell culture medium with no cells (NC), with macrophages (MA) and with osteoclasts (OC); (a) Ca ion concentration; (b) P ion concentration; (c) Ca/P molar ratio; (d) Na ion concentration; (e) K ion concentration and (f) Mg ion concentration. The dashed horizontal lines represent the corresponding basal ion concentration in the cell culture medium: 2.05 ± 0.19 mM for Ca, 1.29 ± 0.13 mM for P, 1.59 ± 0.07 for Ca/P molar ratio, 146.88 ± 0.94 mM for Na, 6.01 ± 0.13 mM for K and 0.86 ± 0.02 mM for Mg. Error bars stand for standard deviations (n = 6). Relative comparisons with the Bonferroni correction are indicated by: ***(p < 0.001) and NS (non-significant).