Fig. 9.

(a) Mean resorbed thickness after 24 h of cell experiments with cell culture medium with no cells (NC), with macrophages (MA) and with osteoclasts (OC) on all β-TCP cylinders from all batches (CaP1: Ca/P = 1.496, CaP2: Ca/P = 1.497, CaP3: Ca/P = 1.497, CaP4: Ca/P = 1.498, CaP5: Ca/P = 1.500 and CaP6: Ca/P = 1.502). The mean surface roughness (Ra) of the cylinders before immersion is 4.5 ± 1.3 nm. (b) Mean resorbed thickness of all batches of β-TCP cylinders (CaP1 to CaP6) in contact with osteoclasts as a function of their Ca/P molar ratio. The dashed line represents the linear positive correlation (Pearson's coefficient r = 0.967; R² = 0.935; p = 0.007; y = 6.086x – 9.054) between the mean resorbed thickness and Ca/P molar ratios ≤ 1.500. The colour code represents the phases quantified by the XRD analysis: orange for β-TCP + β-CPP, green for β-TCP and blue for β-TCP + HA. To allow for comparisons, data were normalized to the mean osteoclastic values from each repetition of the cell experiment. Error bars stand for standard deviations: n = 6. Relative comparisons with the Bonferroni correction are indicated by: ***(p < 0.001), *(p < 0.05) and NS (non-significant).