FIGURE 3.

Serum albumin-based nanovehicles as nanoprobes for cancer diagnosis. (A) TEM image of the synthesized FeS@BSA QDs. (B) TEM image of FeS synthesized without BSA. (C) In vitro T₁-weighted magnetic resonance (MR) images and photoacoustic (PA) images of FeS@BSA QDs at various concentrations. (D) Time-dependent T₁-weighted MR images, PA, and ultrasound (US) images of tumor before and after i.v. administration of FeS@BSA QDs. Reproduced with permission from Yang et al. (2020). Copyright 2020, Elsevier. (E) The 3D MSOT images of orthotopic liver tumor upon i.v. administration of BH-NO₂@BSA. (F) The NIR-I/NIR-II fluorescence images and white-light photographs of a mouse with exposed liver and orthotopic liver tumor at the state of pre-excision, post-excision 1, and post-excision 2. The yellow, green, and pink arrows point to the orthotopic liver tumor, the excised tumor, and the excised residual tumor, respectively. Reproduced with permission from Zeng et al. (2020). Copyright 2020, American Chemical Society.